Corpus ID: 21627833

Inflammatory process in murine lymphocytic choriomeningitis is maximal in H-2K or H-2D compatible interactions.

@article{Doherty1976InflammatoryPI,
  title={Inflammatory process in murine lymphocytic choriomeningitis is maximal in H-2K or H-2D compatible interactions.},
  author={P. Doherty and M. Dunlop and C. Parish and R. Zinkernagel},
  journal={Journal of immunology},
  year={1976},
  volume={117 1},
  pages={
          187-90
        }
}
Capacity to transfer adoptively fatal lymphocytic choriomeningitis (LCM) to immunosuppressed, virus-infected recipients is a property of H-2 compatible, non-Ig-bearing virus-immune lymphocytes. Severe meningitis is recognized when donor and recipient share at least one allele at either H-2K or H-2D. Presence of unshared H-2 genes is not obviously inhibitory, and identity at the immune response (Ir) region of the H-2 gene complex is neither sufficient nor necessary. The same constraint applies… Expand
70 Citations
Participation of Cyclophosphamide‐Resistant T Cells in Murine Lymphocytic Choriomeningitis
Influence of non-major histocompatibility complex differences on the severity of lymphocytic choriomeningitis
...
1
2
3
4
5
...