Inflammatory monocytes are potent antitumor effectors controlled by regulatory CD4+ T cells.

@article{Pommier2013InflammatoryMA,
  title={Inflammatory monocytes are potent antitumor effectors controlled by regulatory CD4+ T cells.},
  author={Arnaud Pommier and Alexandra Audemard and Aur{\'e}lie Durand and Ren{\'e}e Lengagne and Arnaud Delpoux and Bruno Martin and Laetitia Douguet and Armelle Le Campion and Masashi Kato and M Avril and C{\'e}dric Auffray and Bruno Lucas and Armelle Pr{\'e}vost-Blondel},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2013},
  volume={110 32},
  pages={13085-90}
}
The present study evaluates the impact of immune cell populations on metastatic development in a model of spontaneous melanoma [mice expressing the human RET oncogene under the control of the metallothionein promoter (MT/ret mice)]. In this model, cancer cells disseminate early but remain dormant for several weeks. Then, MT/ret mice develop cutaneous… CONTINUE READING