Inflammatory mediators in gastroesophageal reflux disease: impact on esophageal motility, fibrosis, and carcinogenesis.

@article{Rieder2010InflammatoryMI,
  title={Inflammatory mediators in gastroesophageal reflux disease: impact on esophageal motility, fibrosis, and carcinogenesis.},
  author={F Rieder and Piero Biancani and Karen M Harnett and Lisa M. Yerian and Gary W. Falk},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2010},
  volume={298 5},
  pages={G571-81}
}
Gastroesophageal reflux disease (GERD) is one of the most common problems in clinical practice today. It is widely believed that functional and structural abnormalities of the gastroesophageal junction as well as an abnormal exposure to gastroduodenal contents are the main contributors to its pathogenesis. Novel findings of the inflammatory process in GERD suggest a far more complex process involving multifaceted inflammatory mechanisms. This review summarizes knowledge about the expression of… CONTINUE READING
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