Inflammatory mediators and their influence on haemostasis.

  title={Inflammatory mediators and their influence on haemostasis.},
  author={Antonio Vasco Salgado and J L B{\'o}veda and Jasone Monasterio and Rosa Mar{\'i}a Segura and M. Lourdes Mourelle and J G{\'o}mez-Jim{\'e}nez and Rosa Peracaula},
  volume={24 2},
Sepsis is the most important cause of mortality in the Intensive Care Units. At present, sepsis is understood to be the inflammatory response of the host to infection, rather than a direct effect of microbial aggression. From the clinical standpoint, this inflammatory response is known as systemic inflammatory response syndrome (SIRS). Pathophysiologically, SIRS is characterized by the activation of several groups of cell (monocytes/macrophages, PMNs, and endothelial cells) and by the release… CONTINUE READING