Inflammatory mediator removal by zero-balance ultrafiltration during cardiopulmonary bypass.

@article{Tallman2002InflammatoryMR,
  title={Inflammatory mediator removal by zero-balance ultrafiltration during cardiopulmonary bypass.},
  author={Richard Tallman and Mark Dumond and David R Brown},
  journal={Perfusion},
  year={2002},
  volume={17 2},
  pages={
          111-5
        }
}
The abnormal conditions to which blood is subjected during cardiopulmonary bypass (CPB) trigger an activation of the inflammatory response in all patients to varying degrees. Both complement activation and the release of cytokines characterize this response. Most inflammatory mediators have a molecular weight that is below the membrane pore size of commonly used ultrafilters, which should allow them to be freely filtered. However, some mediators have been shown to fail to cross through the… CONTINUE READING
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