Inflammatory intrathecal profiles and cortical damage in multiple sclerosis

@article{Magliozzi2018InflammatoryIP,
  title={Inflammatory intrathecal profiles and cortical damage in multiple sclerosis},
  author={Roberta Magliozzi and Owain W. Howell and Richard S. Nicholas and Carolina Cruciani and Marco Castellaro and Chiara Romualdi and Stefania Rossi and Marco Pitteri and Maria Donata Benedetti and Alberto Gajofatto and Francesca Benedetta Pizzini and Stefania Montemezzi and Sarah Rasia and Ruggero Capra and Alessandra Bertoldo and Francesco Facchiano and Salvatore Monaco and Richard Reynolds and Massimiliano Calabrese},
  journal={Annals of Neurology},
  year={2018},
  volume={83}
}
Gray matter (GM) damage and meningeal inflammation have been associated with early disease onset and a more aggressive disease course in multiple sclerosis (MS), but can these changes be identified in the patient early in the disease course? 
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