Inflammatory cytokines in acute ischemic stroke.

  title={Inflammatory cytokines in acute ischemic stroke.},
  author={Antonino Tuttolomondo and Domenico Di Raimondo and Riccardo di Sciacca and Ant{\'o}nio Pinto and Giuseppe Licata},
  journal={Current pharmaceutical design},
  volume={14 33},
Three major cytokines, namely, tumor necrosis factor (TNF-alpha), interleukin (IL)-1, and IL-6 are produced by cultured brain cells after various stimuli such as ischemia. Neurones, astrocytes, microglia and oligodendrocytes can produce inflammatory mediators, and cytokine receptors are expressed constitutionally throughout the Central Nervous System (CNS), albeit at low levels. Cytokines are involved in virtually every facet of stroke and they have numerous pro-inflammatory and pro-coagulant… CONTINUE READING
92 Citations
0 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 92 extracted citations

Similar Papers

Loading similar papers…