Inflammatory cytokine responses in juvenile chronic arthritis.

  title={Inflammatory cytokine responses in juvenile chronic arthritis.},
  author={Megan P Rooney and J David and Janette Symons and Francesco S di Giovine and Hemlata Varsani and Patricia Woo},
  journal={British journal of rheumatology},
  volume={34 5},
The inflammatory cytokines interleukin 1 beta (IL-1 beta) interleukin 6 (IL-6), tumour necrosis factor alpha (TNF alpha) and the anti-inflammatory peptide--the interleukin 1 (IL-1) receptor antagonist--were measured in the plasma of children with juvenile chronic arthritis (JCA). In the two subgroups studied (polyarticular JCA and systemic JCA), there was good correlation between laboratory measures of disease activity C-reactive protein (CRP), erythrocyte sedimentation rate and clinical scores… CONTINUE READING


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