Inflammatory cytokine response in patients with septic shock secondary to generalized peritonitis.

@article{Rich2000InflammatoryCR,
  title={Inflammatory cytokine response in patients with septic shock secondary to generalized peritonitis.},
  author={Florence C. Rich{\'e} and Bernard Cholley and Yves Panis and M. J. Laisn{\'e} and C G Briard and Anne Marie Graulet and Jean Gueris and Patrice D Valleur},
  journal={Critical care medicine},
  year={2000},
  volume={28 2},
  pages={
          433-7
        }
}
OBJECTIVES The aims of this study were the following: a) to assess the proinflammatory cytokine (tumor necrosis factor [TNF]-alpha, interleukin [IL]-1, and IL-6) response in patients with septic shock secondary to generalized peritonitis; and b) to evaluate the influence of bacteremic status, type of peritonitis (acute perforation or postoperative), and peritoneal microbial status (mono- or polymicrobial) on cytokine expression and mortality. DESIGN Prospective study. SETTING Surgical… CONTINUE READING
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