Inflammatory changes and breakdown of microvascular integrity in early human immunodeficiency virus dementia

@article{Avison2004InflammatoryCA,
  title={Inflammatory changes and breakdown of microvascular integrity in early human immunodeficiency virus dementia},
  author={Malcolm Avison and Avindra Nath and Robin Greene-Avison and Frederick A. Schmitt and Rodney A. Bales and As’ad Ethisham and Richard N. Greenberg and Joseph R. Berger},
  journal={Journal of NeuroVirology},
  year={2004},
  volume={10},
  pages={223-232}
}
Increased postcontrast enhancement in contrast-enhanced magnetic resonance imaging (CE-MRI) of the central nervous system (CNS) is a predictor of human immunodeficiency virus (HIV) dementia severity in HIV-infected subjects. The present study confirms this earlier finding in a mildly impaired patient cohort, and demonstrates that the increased postcontrast enhancement is correlated with increased cerebrospinal fluid (CSF) levels of monocyte chemoattractant protein (MCP)-1, an inflammatory… CONTINUE READING
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