Inflammatory cells degrade inter-alpha inhibitor to liberate urinary proteinase inhibitors.

Abstract

The relationship between inter-alpha inhibitor (I alpha I) and urinary proteinase inhibitor (UPI) was examined by comparing purified UPI with a proteolytic fragment of I alpha I (I'), and by demonstrating that inflammatory cells produce similar fragments under physiologic conditions. Purified I', derived by chymotrypsin digestion of I alpha I, was similar… (More)

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Cite this paper

@article{Pratt1989InflammatoryCD, title={Inflammatory cells degrade inter-alpha inhibitor to liberate urinary proteinase inhibitors.}, author={Christine Pratt and Mark W. Swaim and Salvatore Vincent Pizzo}, journal={Journal of leukocyte biology}, year={1989}, volume={45 1}, pages={1-9} }