Inflammatory bowel disorders: gene therapy solutions.

  title={Inflammatory bowel disorders: gene therapy solutions.},
  author={Stefan Wirtz and Markus F Neurath},
  journal={Current opinion in molecular therapeutics},
  volume={5 5},
Current options to treat inflammatory bowel diseases (IBDs) are often associated with undesired side effects, have limited therapeutic benefit for many patients and do not lead to a complete restoration of the mucosal immune balance. Recent research progress in the pathogenesis of IBDs has widely broadened our understanding of the complex nature of these immunological disorders and identified new potential therapeutic targets. New insights into the molecular mechanisms underlying IBDs may now… CONTINUE READING