Inflammatory bowel disease in rats: bacterial and chemical interaction.

Abstract

AIM To develop a novel model of colitis in rats, using a combination of iodoacetamide and enteropathogenic E. coli (EPEC), and to elucidate the pathophysiologic processes implicated in the development of ulcerative colitis (UC). METHODS Male Sprague-Dawley rats (n = 158) were inoculated intrarectally on a weekly basis with 4 different combinations: (a) 1… (More)

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@article{Hussein2008InflammatoryBD, title={Inflammatory bowel disease in rats: bacterial and chemical interaction.}, author={Inaya-Abdallah Hajj Hussein and Rania A. Tohme and Kassem A. Barada and Mostafa Hassan Mostafa and Jean-Noel Freund and Rosalyn A. Jurjus and Walid Karam and Abdo R. Jurjus}, journal={World journal of gastroenterology}, year={2008}, volume={14 25}, pages={4028-39} }