Inflammatory bowel disease: clinical aspects and established and evolving therapies

@article{Baumgart2007InflammatoryBD,
  title={Inflammatory bowel disease: clinical aspects and established and evolving therapies},
  author={D. Baumgart and W. Sandborn},
  journal={The Lancet},
  year={2007},
  volume={369},
  pages={1641-1657}
}
Crohn's disease and ulcerative colitis are two idiopathic inflammatory bowel disorders. In this paper we discuss the current diagnostic approach, their pathology, natural course, and common complications, the assessment of disease activity, extraintestinal manifestations, and medical and surgical management, and provide diagnostic and therapeutic algorithms. We critically review the evidence for established (5-aminosalicylic acid compounds, corticosteroids, immunomodulators, calcineurin… Expand

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References

SHOWING 1-10 OF 187 REFERENCES
Review article: systemic and topical steroids in inflammatory bowel disease.
Oral p38 mitogen-activated protein kinase inhibition with BIRB 796 for active Crohn's disease: a randomized, double-blind, placebo-controlled trial.
  • S. Schreiber, B. Feagan, +11 authors J. Steffgen
  • Medicine
  • Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
  • 2006
...
1
2
3
4
5
...