Inflammatory Mediators and Modulation of Blood–Brain Barrier Permeability

@article{Abbott2004InflammatoryMA,
  title={Inflammatory Mediators and Modulation of Blood–Brain Barrier Permeability},
  author={N. Abbott},
  journal={Cellular and Molecular Neurobiology},
  year={2004},
  volume={20},
  pages={131-147}
}
  • N. Abbott
  • Published 2004
  • Medicine, Biology
  • Cellular and Molecular Neurobiology
  • Abstract1. Unlike some interfaces between the blood and the nervous system (e.g., nerve perineurium), the brain endothelium forming the blood–brain barrier can be modulated by a range of inflammatory mediators. The mechanisms underlying this modulation are reviewed, and the implications for therapy of the brain discussed.2. Methods for measuring blood–brain barrier permeability in situ include the use of radiolabeled tracers in parenchymal vessels and measurements of transendothelial resistance… CONTINUE READING
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