Inflammatory Bowel Disease: Effects on Bone and Mechanisms.

  title={Inflammatory Bowel Disease: Effects on Bone and Mechanisms.},
  author={Francisco Augusto Sylvester},
  journal={Advances in experimental medicine and biology},
Inflammatory bowel disease (IBD) is associated with decreased bone mass and alterations in bone geometry from the time of diagnosis, before anti-inflammatory therapy is instituted. Deficits in bone mass can persist despite absence of symptoms of active IBD. The effects of IBD on the skeleton are complex. Protein-calorie malnutrition, inactivity, hypogonadism, deficits in calcium intake and vitamin D consumption and synthesis, stunted growth in children, decreased skeletal muscle mass, and… CONTINUE READING