Inflammatory Biomarkers Predict Heart Failure Severity and Prognosis in Patients With Heart Failure With Preserved Ejection Fraction: A Holistic Proteomic Approach.

@article{Hage2017InflammatoryBP,
  title={Inflammatory Biomarkers Predict Heart Failure Severity and Prognosis in Patients With Heart Failure With Preserved Ejection Fraction: A Holistic Proteomic Approach.},
  author={Camilla Hage and Erik Micha{\"e}lsson and Cecilia M Linde and Erwan Donal and J L Daubert and Li-ming Gan and Lars H. Lund},
  journal={Circulation. Cardiovascular genetics},
  year={2017},
  volume={10 1}
}
BACKGROUND Underlying mechanisms in heart failure (HF) with preserved ejection fraction remain unknown. We investigated cardiovascular plasma biomarkers in HF with preserved ejection fraction and their correlation to diastolic dysfunction, functional class, pathophysiological processes, and prognosis. METHODS AND RESULTS In 86 stable patients with HF and EF ≥45% in the Karolinska Rennes (KaRen) biomarker substudy, biomarkers were quantified by a multiplex immunoassay. Orthogonal projection to… CONTINUE READING

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