Inflammation is responsible for the development of wound-induced tumors in chickens infected with Rous sarcoma virus.

@article{MartinsGreen1994InflammationIR,
  title={Inflammation is responsible for the development of wound-induced tumors in chickens infected with Rous sarcoma virus.},
  author={Manuela Martins-Green and Nancy Boudreau and Mina J. Bissell},
  journal={Cancer research},
  year={1994},
  volume={54 16},
  pages={4334-41}
}
When newly hatched chicks are given injections of Rous sarcoma virus, a tumor develops at the site of injection. In spite of the presence of the virus in the blood, no other tumors are found distant from the site of inoculation during the life span of the animal (4-6 weeks). However, if a wound is made away from the primary tumor, a tumor develops at the site of wounding. Work in our laboratory showed previously that these wound tumors do not develop as a result of metastasis, therefore… CONTINUE READING

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