Inflammation-induced subventricular zone dysfunction leads to olfactory deficits in a targeted mouse model of multiple sclerosis.

@article{Tepavevi2011InflammationinducedSZ,
  title={Inflammation-induced subventricular zone dysfunction leads to olfactory deficits in a targeted mouse model of multiple sclerosis.},
  author={Vanja Tepav{\vc}evi{\'c} and Françoise Lazarini and Clara Alfaro-Cervell{\'o} and Christophe Kerninon and Kazuaki Yoshikawa and Jose Manuel Garc{\'i}a-Verdugo and Pierre-Marie Lledo and Brahim Nait-Oumesmar and Anne Baron-Van Evercooren},
  journal={The Journal of clinical investigation},
  year={2011},
  volume={121 12},
  pages={4722-34}
}
Neural stem cells (NSCs) persist in defined brain niches, including the subventricular zone (SVZ), throughout adulthood and generate new neurons destined to support specific neurological functions. Whether brain diseases such as multiple sclerosis (MS) are associated with changes in adult NSCs and whether this might contribute to the development and/or persistence of neurological deficits remains poorly investigated. We examined SVZ function in mice in which we targeted an MS-like pathology to… CONTINUE READING
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Activation of the subventricular zone in multiple sclerosis: evidence for early glial progenitors

  • B Nait-Oumesmar
  • Proc Natl Acad Sci U S A
  • 2007
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