Inflammation in the pathogenesis of age-related macular degeneration.

  title={Inflammation in the pathogenesis of age-related macular degeneration.},
  author={Atsuhiro Kanda and Gonçalo R. Abecasis and Anand Swaroop},
  journal={The British journal of ophthalmology},
  volume={92 4},
Age-related macular degeneration (AMD), the leading cause of blindness in the elderly, is a complex disease to study because of the potential role of demographic, environmental, and other systemic risk factors, such as age, sex, race, light exposure, diet, smoking, and underlying cardiovascular disease which may contribute to the pathogenesis of this disease. Recently, single nucleotide polymorphisms, DNA sequence variations found within the complement Factor H gene, have been found to be… CONTINUE READING