Inflammation in the early stages of neurodegenerative pathology.

  title={Inflammation in the early stages of neurodegenerative pathology.},
  author={Preeti J. Khandelwal and Alexander M. Herman and Charbel Moussa},
  journal={Journal of neuroimmunology},
  volume={238 1-2},
Inflammation is secondary to protein accumulation in neurodegenerative diseases, including Alzheimer's, Parkinson's and Amyotrophic Lateral Sclerosis. Emerging evidence indicate sustained inflammatory responses, involving microglia and astrocytes in animal models of neurodegeneration. It is unknown whether inflammation is beneficial or detrimental to disease progression and how inflammatory responses are induced within the CNS. Persistence of an inflammatory stimulus or failure to resolve… CONTINUE READING
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