Inflammation in atherosclerosis

@article{Libby2002InflammationIA,
  title={Inflammation in atherosclerosis},
  author={P. Libby},
  journal={Nature},
  year={2002},
  volume={420},
  pages={868-874}
}
  • P. Libby
  • Published 2002
  • Medicine
  • Nature
  • Abundant data link hypercholesterolaemia to atherogenesis. However, only recently have we appreciated that inflammatory mechanisms couple dyslipidaemia to atheroma formation. Leukocyte recruitment and expression of pro-inflammatory cytokines characterize early atherogenesis, and malfunction of inflammatory mediators mutes atheroma formation in mice. Moreover, inflammatory pathways promote thrombosis, a late and dreaded complication of atherosclerosis responsible for myocardial infarctions and… CONTINUE READING

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