Inflammation in asthma: the cornerstone of the disease and target of therapy.

@article{Busse1998InflammationIA,
  title={Inflammation in asthma: the cornerstone of the disease and target of therapy.},
  author={William W. Busse},
  journal={The Journal of allergy and clinical immunology},
  year={1998},
  volume={102 4 Pt 2},
  pages={
          S17-22
        }
}
Asthma is a chronic disease associated with variable levels of airflow obstruction. Considerable evidence has been obtained to show that airway inflammation is a major factor in the pathogenesis of asthma in associated bronchial hyperresponsiveness, and in the level of disease severity. The inflammatory pattern in asthma is multicellular in nature, with mast cells, neutrophils, eosinophils, T lymphocytes, and epithelial cells participating in the response. Furthermore, it is known that… CONTINUE READING

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