Inflammation-associated enterotypes, host genotype, cage and inter-individual effects drive gut microbiota variation in common laboratory mice

@inproceedings{Hildebrand2012InflammationassociatedEH,
  title={Inflammation-associated enterotypes, host genotype, cage and inter-individual effects drive gut microbiota variation in common laboratory mice},
  author={Falk Hildebrand and Thi Loan Anh Nguyen and Brigitta M. Brinkman and Roberto Garcia Yunta and B{\'e}n{\'e}dicte Cauwe and Peter Vandenabeele and Adrian Liston and Jeroen Raes},
  booktitle={Genome Biology},
  year={2012}
}
Murine models are a crucial component of gut microbiome research. Unfortunately, a multitude of genetic backgrounds and experimental setups, together with inter-individual variation, complicates cross-study comparisons and a global understanding of the mouse microbiota landscape. Here, we investigate the variability of the healthy mouse microbiota of five common lab mouse strains using 16S rDNA pyrosequencing. We find initial evidence for richness-driven, strain-independent murine enterotypes… CONTINUE READING
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