Inflammation-associated CNS pathways to fatigue in breast cancer patients

  title={Inflammation-associated CNS pathways to fatigue in breast cancer patients},
  author={J. Felger and M. Treadway and E. Haroon and Z. Li and M. Torres and A. Miller},
  journal={Brain, Behavior, and Immunity},
Breast cancer patients (∼40%) experience debilitating cancer-related fatigue (CRF), and efficacious treatment options are limited due in part to lack of understanding of the underlying pathophysiology. One promising avenue for treatment discovery is investigation of inflammation effects on CNS pathways involved in motivation and motor activity that may contribute to fatigue. Previous work shows that fatigue both during and after breast cancer treatment is associated with increased inflammation… Expand
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