Inflammation and prevention of epileptogenesis

@article{Ravizza2011InflammationAP,
  title={Inflammation and prevention of epileptogenesis},
  author={Teresa Ravizza and Silvia Balosso and Annamaria Vezzani},
  journal={Neuroscience Letters},
  year={2011},
  volume={497},
  pages={223-230}
}
CNS injuries such as trauma, stroke, viral infection, febrile seizures, status epilepticus occurring either in infancy or during a lifetime are considered common risk factors for developing epilepsy. Long term CNS inflammation develops rapidly after these events, suggesting that a pro-inflammatory state in the brain might play a role in the development of the epileptic process. This hypothesis is corroborated by two main lines of evidence: (1) the upregulation of pro-inflammatory signals during… CONTINUE READING

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