Inflammation and metabolic disorders

@article{Hotamisligil2006InflammationAM,
  title={Inflammation and metabolic disorders},
  author={G{\"o}khan S Hotamisligil},
  journal={Nature},
  year={2006},
  volume={444},
  pages={860-867}
}
Metabolic and immune systems are among the most fundamental requirements for survival. Many metabolic and immune response pathways or nutrient- and pathogen-sensing systems have been evolutionarily conserved throughout species. As a result, immune response and metabolic regulation are highly integrated and the proper function of each is dependent on the other. This interface can be viewed as a central homeostatic mechanism, dysfunction of which can lead to a cluster of chronic metabolic… CONTINUE READING

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