Inflammation and insulin resistance are independently related to all-cause of death and cardiovascular events in Japanese patients with type 2 diabetes mellitus.

@article{Matsumoto2003InflammationAI,
  title={Inflammation and insulin resistance are independently related to all-cause of death and cardiovascular events in Japanese patients with type 2 diabetes mellitus.},
  author={Kazunari Matsumoto and Yasunori Sera and Yasuyo Abe and Yukitaka Ueki and Tan Tominaga and Seibei Miyake},
  journal={Atherosclerosis},
  year={2003},
  volume={169 2},
  pages={317-21}
}
Insulin resistance (IR)/hyperinsulinemia and low-grade inflammation (high-sensitivity C-reactive protein [hs-CRP]) can predict cardiovascular disease. However, because IR and inflammation (IF) have not been evaluated simultaneously, it is not known whether IR and IF are independently related to cardiovascular disease. Furthermore, the combined effect of IR and IF on the prediction of cardiovascular disease is presently unknown. Thus, we measured insulin sensitivity (K index of the insulin… CONTINUE READING
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