Inflammation and brain edema: new insights into the role of chemokines and their receptors.

@article{Stamatovic2006InflammationAB,
  title={Inflammation and brain edema: new insights into the role of chemokines and their receptors.},
  author={Svetlana M. Stamatovic and Oliver B Dimitrijevic and Richard F. Keep and Anuska V. Andjelkovic},
  journal={Acta neurochirurgica. Supplement},
  year={2006},
  volume={96},
  pages={
          444-50
        }
}
Brain edema is associated with a variety of neuropathological conditions such as brain trauma, ischemic and hypoxic brain injury, central nervous system infection, acute attacks of multiple sclerosis, and brain tumors. A common finding is an inflammatory response, which may have a significant impact on brain edema formation. One critical event in the development of brain edema is blood-brain barrier (BBB) breakdown, which may be initiated and regulated by several proinflammatory mediators… CONTINUE READING
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