Inflammation and Immune Response in COPD: Where Do We Stand?

@inproceedings{Rovina2013InflammationAI,
  title={Inflammation and Immune Response in COPD: Where Do We Stand?},
  author={Nikoletta Rovina and Antonia Koutsoukou and Nikolaos G Koulouris},
  booktitle={Mediators of inflammation},
  year={2013}
}
  • Nikoletta Rovina, Antonia Koutsoukou, Nikolaos G Koulouris
  • Published in Mediators of inflammation 2013
  • Biology, Medicine
  • Increasing evidence indicates that chronic inflammatory and immune responses play key roles in the development and progression of COPD. Recent data provide evidence for a role in the NLRP3 inflammasome in the airway inflammation observed in COPD. Cigarette smoke activates innate immune cells by triggering pattern recognition receptors (PRRs) to release "danger signal". These signals act as ligands to Toll-like receptors (TLRs), triggering the production of cytokines and inducing innate… CONTINUE READING

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