Inflammation after axonal injury has conflicting consequences for recovery of function: Rescue of spared axons is impaired but regeneration is supported

@article{Hirschberg1994InflammationAA,
  title={Inflammation after axonal injury has conflicting consequences for recovery of function: Rescue of spared axons is impaired but regeneration is supported},
  author={David L. Hirschberg and Eti Yoles and Michael Belkin and Michal Schwartz},
  journal={Journal of Neuroimmunology},
  year={1994},
  volume={50},
  pages={9-16}
}
Neural injury leads to tissue damage beyond that caused by the initial lesion, mainly as a result of a chain of autodestructive events triggered by the trauma. These events apparently include the activation of immune-derived cells and their products, as treatment with anti-inflammatory agents, such as corticosteroids, limits the damage and thus improves recovery. On the other hand, immune-derived substances, such as cytokines, are thought to play an important role in post-traumatic axonal… CONTINUE READING

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