Inflammation activates the CXCL16 pathway to contribute to tubulointerstitial injury in diabetic nephropathy.

Abstract

Inflammation and lipid disorders play crucial roles in synergistically accelerating the progression of diabetic nephropathy (DN). In this study we investigated how inflammation and lipid disorders caused tubulointerstitial injury in DN in vivo and in vitro. Diabetic db/db mice were injected with 10% casein (0.5 mL, sc) every other day for 8 weeks to cause… (More)
DOI: 10.1038/aps.2017.177

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