Inflammation-Related Effects of Diesel Engine Exhaust Particles: Studies on Lung Cells In Vitro

@inproceedings{Schwarze2013InflammationRelatedEO,
  title={Inflammation-Related Effects of Diesel Engine Exhaust Particles: Studies on Lung Cells In Vitro},
  author={P. E. Schwarze and Annike Irene Totlandsdal and Marit L{\aa}g and Magne Refsnes and J\orn A Holme and Johan \Ovrevik},
  booktitle={BioMed research international},
  year={2013}
}
Diesel exhaust and its particles (DEP) have been under scrutiny for health effects in humans. In the development of these effects inflammation is regarded as a key process. Overall, in vitro studies report similar DEP-induced changes in markers of inflammation, including cytokines and chemokines, as studies in vivo. In vitro studies suggest that soluble extracts of DEP have the greatest impact on the expression and release of proinflammatory markers. Main DEP mediators of effects have still not… CONTINUE READING
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