Inflammation Modulatory Phorbol Esters from the Seeds of Aquilaria malaccensis.

  title={Inflammation Modulatory Phorbol Esters from the Seeds of Aquilaria malaccensis.},
  author={Vitthal D. Wagh and Michal Korinek and I-Wen Lo and Yu-Ming Hsu and Shu-li Chen and H O Hsu and Tsong-Long Hwang and Yang-Chang Wu and Bing-Hung Chen and Yuan-Bin Cheng and F. -H. Chang},
  journal={Journal of natural products},
  volume={80 5},
The tree Aquilaria malaccensis is a valuable source of agarwood, which is used in herbal medicinal preparations. Phytochemical research on A. malaccensis seeds has led to the isolation of four new phorbol esters (1-4), two known phorbol esters (5, isolated from Nature for the first time, and 6), and two known glycerides (7 and 8). The structures of these isolates were elucidated by means of spectroscopic data interpretation. The inflammation-modulatory activities of the isolates on elastase… CONTINUE READING
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