Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link?

@article{Yudkin2000InflammationOS,
  title={Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link?},
  author={John S. Yudkin and Meena Kumari and Steve E Humphries and Vidya Mohamed-Ali},
  journal={Atherosclerosis},
  year={2000},
  volume={148 2},
  pages={209-14}
}
There is mounting evidence that inflammation plays a role in the development of coronary heart disease (CHD). Observations have been made linking the presence of infections in the vessel wall with atherosclerosis, and epidemiological data also implicate infection in remote sites in the aetiology of CHD. In this article we propose a key role for the proinflammatory cytokine interleukin-6 (IL-6) in several mechanisms that contribute to the development of CHD. IL-6 is a powerful inducer of the… CONTINUE READING
Highly Influential
This paper has highly influenced 37 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 628 extracted citations

Similar Papers

Loading similar papers…