Inflammation, metaflammation and immunometabolic disorders

@article{Hotamisligil2017InflammationMA,
  title={Inflammation, metaflammation and immunometabolic disorders},
  author={G{\"o}khan S Hotamisligil},
  journal={Nature},
  year={2017},
  volume={542},
  pages={177-185}
}
Proper regulation and management of energy, substrate diversity and quantity, as well as macromolecular synthesis and breakdown processes, are fundamental to cellular and organismal survival and are paramount to health. Cellular and multicellular organization are defended by the immune response, a robust and critical system through which self is distinguished from non-self, pathogenic signals are recognized and eliminated, and tissue homeostasis is safeguarded. Many layers of evolutionarily… CONTINUE READING
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