Inflammation, genes and zinc in Alzheimer's disease.

  title={Inflammation, genes and zinc in Alzheimer's disease.},
  author={Sonya Vasto and G Candore and Florinda List{\`i} and Carmela Rita Balistreri and Giuseppina Colonna-Romano and Marco Malavolta and Domenico Lio and Domenico Nuzzo and Eugenio Mocchegiani and Danilo Di Bona and Calogero Caruso},
  journal={Brain research reviews},
  volume={58 1},
Alzheimer's disease (AD) is a heterogeneous and progressive neurodegenerative disease which in Western society mainly accounts for clinical dementia. AD has been linked to inflammation and metal biological pathway. Neuro-pathological hallmarks are senile plaques, resulting from the accumulation of several proteins and an inflammatory reaction around deposits of amyloid, a fibrillar protein, Abeta, product of cleavage of a much larger protein, the beta-amyloid precursor protein (APP) and… CONTINUE READING
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