Inflammation, a key event in cancer development.

  title={Inflammation, a key event in cancer development.},
  author={Haitian Lu and Weiming Ouyang and Chuanshu Huang},
  journal={Molecular cancer research : MCR},
  volume={4 4},
Several recent studies have identified nuclear factor-kappaB as a key modulator in driving inflammation to cancers. Besides this transcription factor, essential in regulating inflammation and cancer development, an inflammatory microenvironment inhabiting various inflammatory cells and a network of signaling molecules are also indispensable for the malignant progression of transformed cells, which is attributed to the mutagenic predisposition of persistent infection-fighting agents at sites of… CONTINUE READING
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