Inflammasomes in Inflammation-Induced Cancer

@inproceedings{Lin2017InflammasomesII,
  title={Inflammasomes in Inflammation-Induced Cancer},
  author={Chu Lin and Jun Zhang},
  booktitle={Front. Immunol.},
  year={2017}
}
The inflammasome is an important multiprotein complex that functions during inflammatory immune responses. The activation of inflammasome will lead to the autoactivation of caspase-1 and subsequent cleavage of proIL-1β and proIL-18, which are key sources of inflammatory manifestations. Recently, the roles of inflammasomes in cancers have been extensively explored, especially in inflammation-induced cancers. In different and specific contexts, inflammasomes exhibit distinct and even contrasting… CONTINUE READING
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