Inflammageing and metaflammation: The yin and yang of type 2 diabetes

@article{Prattichizzo2018InflammageingAM,
  title={Inflammageing and metaflammation: The yin and yang of type 2 diabetes},
  author={Francesco Prattichizzo and Valeria De Nigris and Rosangela Spiga and Elettra Mancuso and Antonio Ceriello},
  journal={Ageing Research Reviews},
  year={2018},
  volume={41},
  pages={1-17}
}
Type 2 diabetes mellitus (T2DM) is characterised by chronic low-grade inflammation, recently referred to as 'metaflammation', a relevant factor contributing to the development of both diabetes and its complications. Nonetheless, 'canonical' anti-inflammatory drugs do not yield satisfactory results in terms of prevention of diabetes progression and of cardiovascular events, suggesting that the causal mechanisms fostering metaflammation deserve further research to identify new druggable targets… CONTINUE READING
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