Infiltration of inflammatory cells through brain endothelium.

  title={Infiltration of inflammatory cells through brain endothelium.},
  author={P Olivier Couraud},
  volume={46 3},
The blood-brain barrier (BBB) restricts exchanges of soluble factors and cells between the blood and the brain, thus playing a crucial role in maintenance of cerebral homeostasis. It is composed of the endothelial cells that line the cerebral capillaries. Cerebral capillaries have a number of distinctive morphological characteristics, including the presence of tight intercellular junctions. Also, the cerebral capillaries are surrounded by astrocytic projections that exert a positive regulatory… CONTINUE READING


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