Infiltration of central nervous system in adult acute myeloid leukaemia.

@article{Pippard1979InfiltrationOC,
  title={Infiltration of central nervous system in adult acute myeloid leukaemia.},
  author={Martin J Pippard and Sheila T. Callender and Phillip Sheldon},
  journal={British medical journal},
  year={1979},
  volume={1 6158},
  pages={227-9}
}
Out of 64 consecutive unselected patients with acute myeloid leukaemia studied during 1973-6, five developed clinical evidence of spread to the central nervous system (CNS). Neuroradiological examination showed cerebral deposits in three, in whom rapid symptomatic relief was obtained with radiotherapy. In two of these patients who developed solid intracranial deposits haematological remission could be reinduced or maintained; they were still alive 86 and 134 weeks later. When patients presented… CONTINUE READING