Infertility in mice infected genitally with a human strain of Chlamydia trachomatis.

@article{Tuffrey1986InfertilityIM,
  title={Infertility in mice infected genitally with a human strain of Chlamydia trachomatis.},
  author={M. Tuffrey and P. Falder and J. Gale and R. Quinn and D. Taylor-Robinson},
  journal={Journal of reproduction and fertility},
  year={1986},
  volume={78 1},
  pages={
          251-60
        }
}
Progesterone-treated C3H and TO mice were inoculated genitally with a human C. trachomatis strain, serovar E, designated N.I. 1 or with 2SP control medium. Of the C3H mice serving as controls 93% had litters by the end of a 6-month period compared to 31% of mice infected with chlamydiae. This infertility could not be explained by tubal occlusion, since the oviducts appeared normal at autopsy. Some of the mice were induced to superovulate. Eggs were never recovered from the oviducts on the… Expand
A proposed mouse model to study male infertility provoked by genital serovar E, Chlamydia trachomatis.
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