Inferring thermodynamic stability relationship of polymorphs from melting data.

  • Liuqi Yu
  • Published 1995 in Journal of pharmaceutical sciences

Abstract

This study investigates the possibility of inferring the thermodynamic stability relationship of polymorphs from their melting data. Thermodynamic formulas are derived for calculating the Gibbs free energy difference (delta G) between two polymorphs and its temperature slope from mainly the temperatures and heats of melting. This information is then used to… (More)

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Cite this paper

@article{Yu1995InferringTS, title={Inferring thermodynamic stability relationship of polymorphs from melting data.}, author={Liuqi Yu}, journal={Journal of pharmaceutical sciences}, year={1995}, volume={84 8}, pages={966-74} }