Inferring sub-cellular localization through automated lexical analysis

  title={Inferring sub-cellular localization through automated lexical analysis},
  author={Rajesh Nair and Burkhard Rost},
  volume={18 Suppl 1},
MOTIVATION The SWISS-PROT sequence database contains keywords of functional annotations for many proteins. In contrast, information about the sub-cellular localization is available for only a few proteins. Experts can often infer localization from keywords describing protein function. We developed LOCkey, a fully automated method for lexical analysis of SWISS-PROT keywords that assigns sub-cellular localization. With the rapid growth in sequence data, the biochemical characterisation of… CONTINUE READING
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