Inferring phylogenies of evolving sequences without multiple sequence alignment


Alignment-free methods, in which shared properties of sub-sequences (e.g. identity or match length) are extracted and used to compute a distance matrix, have recently been explored for phylogenetic inference. However, the scalability and robustness of these methods to key evolutionary processes remain to be investigated. Here, using simulated sequence sets… (More)
DOI: 10.1038/srep06504



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