Inferring parameters shaping amino acid usage in prokaryotic genomes via Bayesian MCMC methods.

Abstract

Molar content of guanine plus cytosine (G + C) and optimal growth temperature (OGT) are main factors characterizing the frequency distribution of amino acids in prokaryotes. Previous work, using multivariate exploratory methods, has emphasized ascertainment of biological factors underlying variability between genomes, but the strength of each identified… (More)

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