Inferring gene regulatory relationships with a high-dimensional robust approach.

Abstract

Gene expression (GE) levels have important biological and clinical implications. They are regulated by copy number alterations (CNAs). Modeling the regulatory relationships between GEs and CNAs facilitates understanding disease biology and can also have values in translational medicine. The expression level of a gene can be regulated by its cis-acting as… (More)
DOI: 10.1002/gepi.22047

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