Inferring gene function from evolutionary change in signatures of translation efficiency

Abstract

The genetic code is redundant, meaning that most amino acids can be encoded by more than one codon. Highly expressed genes tend to use optimal codons to increase the accuracy and speed of translation. Thus, codon usage biases provide a signature of the relative expression levels of genes, which can, uniquely, be quantified across the domains of life. Here… (More)
DOI: 10.1186/gb-2014-15-3-r44

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Cite this paper

@inproceedings{Krisko2013InferringGF, title={Inferring gene function from evolutionary change in signatures of translation efficiency}, author={Anita Krisko and Tea Copic and Toni Gabald{\'o}n and Ben Lehner and Fran Supek}, booktitle={Genome Biology}, year={2013} }