Inferring and validating horizontal gene transfer events using bipartition dissimilarity.

@article{Boc2010InferringAV,
  title={Inferring and validating horizontal gene transfer events using bipartition dissimilarity.},
  author={Alix Boc and Herv{\'e} Philippe and Vladimir Makarenkov},
  journal={Systematic biology},
  year={2010},
  volume={59 2},
  pages={195-211}
}
Horizontal gene transfer (HGT) is one of the main mechanisms driving the evolution of microorganisms. Its accurate identification is one of the major challenges posed by reticulate evolution. In this article, we describe a new polynomial-time algorithm for inferring HGT events and compare 3 existing and 1 new tree comparison indices in the context of HGT identification. The proposed algorithm can rely on different optimization criteria, including least squares (LS), Robinson and Foulds (RF… CONTINUE READING